ginseng extract powder
What is ginseng extract powder
Ginseng is a Araliaceae plant, native to Asia, mainly distributed in China, South Korea and Japan Ginseng has a long medicinal history in China, has the title of “king of herbs” and is also one of the famous “three treasures in Northeast China”.
The medicinal effects of ginseng are introduced in compendium of Materia Medica, Shennong materia medica classic and other works. According to traditional Chinese medicine, ginseng is gentle and mild in nature.
It can replenish the vitality and Qi of spleen and lung. It can also generate fluid and calm the mind. It is often used to treat Qi deficiency, thirst, restlessness, palpitation and forgetfulness, and replenish the spleen and lung.
It has important medicinal value. Modern medical research shows that ginseng can protect the heart, promote hematopoietic function, regulate blood glucose and blood pressure, enhance immunity and so on. Drugs with ginseng as the main component, such as Shenyi capsule and ginseng Jianpi pill, have been put into the market And achieved good curative effect.
China is rich in ginseng resources, ginseng and its The products are exported to all over the world and their medicinal value has been widely recognized
What is Ginseng
Ginseng is a traditional Chinese medicine in China. Its use and efficacy, such as regulation Blood pressure, promoting metabolism and enhancing immunity have long been recorded.
order There are nearly ten species of ginseng found before, of which three are the most common There are ginseng, Panax notoginseng and American ginseng, which are used as medicine and medicine Functional food has great market potential
The bioactive components in ginseng include saponins, polysaccharides and phenols. Ginsenosides have attracted more and more attention because of their anticancer, anti-inflammatory and hypoglycemic effects;
The research on its structure-activity relationship, pharmacodynamics and pharmacokinetic properties is also gradually in-depth. In terms of structure, ginsenosides are composed of steroidal skeleton and sugar groups connected at C3, C6 and C20 positions.
According to different steroidal skeletons, ginsenosides can be divided into three categories, namely dammarane type, oleanol type and octilonol type, of which most ginsenosides belong to dammarane type
What is ginsenoside of ginseng extract powder
Compared with other active ingredients, ginsenosides have been studied more, with clear structure and good drug efficacy Various physical and chemical activities.
In recent years, ginseng polysaccharide is an important component of ginseng to exert its pharmacodynamic activity Ginseng, which has different structural characteristics and different activities, has attracted more and more attention Polysaccharide was reported
What is ginseng polysaccharide of ginseng extract powder
According to the different monosaccharide composition, ginseng polysaccharides are mainly divided into neutral sugar and acid pectin.
Neutral sugars include dextran, arabinogalactan (Ag), etc. Acidic pectin is often heteropolysaccharide and rich in galacturonic acid (Gala). A lot of achievements have been made in the separation, purification, structure and activity of ginseng polysaccharides
What are the classification and structural characteristics of ginseng polysaccharides ginseng extract powder
The neutral sugar in ginseng is mainly composed of amyloid glucan and a small amount of Ag
Through amylase hydrolysis, iodine potassium iodide experiment and Infrared and nuclear magnetic analysis showed that wgpn was mainly composed of amyloid glucan and contained less The relative molecular weight distribution of Ag is wide;
Wgpa-n is mainly composed of amyloid Staphylococcus It is composed of arabinogalactan and arabinogalactan, and its relative molecular weight is small
What is ginseng pectin and ginseng extract powder
Pectin is a polysaccharide rich in gala.
According to the proportion of RHA and Gala, whether it has rare glycosides and the content percentage of Gala Pectin can be divided into type I polyrhamnogalacturonic acid (RG – Ⅰ) and type II polyrhamnogalacturonic acid Rhamnogalacturonic acid (RG – Ⅱ) and polygalacturic acid (Hg)
Why can ginseng polysaccharide have antitumor effect of ginseng extract powder
Acidic sugar is more effective than neutral sugar in increasing the number of splenocytes Into macrophage activity, enhance the sensitivity of red blood cells in the blood. At the same time, acid Sugar can activate T, B lymphocytes and macrophages, while neutral sugar can only activate B Cells and macrophages
Inhibitory activity of ginseng polysaccharide on tumor cell proliferation in vitro It was found that ginseng neutral sugar and ginseng pectin fraction could inhibit tumor Cell proliferation and has a certain effect on cell cycle
Why does ginseng have immunomodulatory effect of ginseng extract powder
Ginseng polysaccharide can increase the weight of spleen and thymus in mice
Ara in its side chain It is closely related to the exertion of immune activity. After removing ara by partial acid hydrolysis,
The effects of wgpa-2-rg on lymphocyte proliferation and no release were significantly reduced, but giant Phagocytosis was enhanced. It shows the structure and immune activity of ginseng pectin Closely related.
Why does ginseng polysaccharide have hypoglycemic effect of ginseng extract powder
Ginseng glycopeptide can reduce blood glucose and blood glucose in mice Increase the content of liver glycogen and pyruvate; Inhibition of lactate dehydrogenase activity; enhance Activities of succinate dehydrogenase, adenylate cyclase and cytochrome oxidase, promoting Aerobic oxidation and insulin release.
In addition, ginseng glycopeptide can increase The content of calmodulin promotes phosphodiesterase activity
Why can ginseng polysaccharide resist radiation of ginseng extract powder
Ginseng polysaccharide can promote peroxidase dismutase and glutamic acid in miceThe expression of cystine peroxidase makes heme oxygenase and non protein sulfhydryl The substance returned to normal and reduced the damage of radiation to the body of mice
Can increase mouse The number of bone marrow cells and micronucleus polychromatic erythrocytes promoted the hematopoietic function of irradiated mice Energy recovery
Why does ginseng polysaccharide have antioxidant effect of ginseng extract powder
Ginseng polysaccharide GP Ⅱ can inhibit superoxide radical, hydroxyl radical and The self oxidation of benzene triol plays an antioxidant role
Ginseng polysaccharide ginsan It can improve the activity of heme oxidase, reduce the level of cytochrome P450 and prolong the The paralysis time induced by chlorobenzoxazole amine will not cause liver injury, and has It has potential antioxidant activity