Technical Specifications
| Parameter | Specification | Testing Method |
|---|---|---|
| Molecular Formula | C6H12O6 | FT-IR Analysis |
| Purity (HPLC) | ≥99.5% | USP ⟨621⟩ |
| Mesh Size | 80-100 μm | Laser Diffraction |
Mechanism of Action
D-Mannose (D-(+)-Mannose) demonstrates dual antibacterial action:
Anti-Adhesion Effect
- ✔️ Blocks Type 1 fimbriae of E.coli
- ✔️ Reduces bacterial adhesion by 82% (in vitro)
Biofilm Disruption
- ✔️ Inhibits biofilm formation at 2mg/mL
- ✔️ Enhances antibiotic efficacy 3-5X
Clinical Validation
2023 RCT (n=450) results:
Commercial Applications
Dietary Supplements
- • Optimal dosage: 500-2000mg/day
- • Synergy with Cranberry PACs
Pharmaceuticals
- • Excipient for UTI drugs
- • Co-formulated with Fosfomycin
Specification
| Item | Specification |
|---|---|
| Product Name | D-Mannose |
| CAS No | 3458-28-4 |
| EINECS Number | 222-392-4 |
| Chemical Formula | C₆H₁₂O₆ |
| Appearance | White or off-white powder |
| Assay (Purity) | ≥ 98% |
| Optical Rotation | +13.5° to +15.5° |
| pH (5% Solution) | 4.0 - 7.0 |
| Moisture Content | ≤ 0.5% |
| Ash Content | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Lead (Pb) | ≤ 1 ppm |
| Total Plate Count | < 1,000 CFU/g |
| Yeast and Mold | < 100 CFU/g |
| E. Coli | Not detected |
| Salmonella | Not detected |
| Solubility | Soluble in water |
| Application | Suitable for dietary supplements, health foods, urinary tract health, etc. |
| Packaging | 1 kg/bag, 25 kg/drum, or customized packaging |
| Storage | Store in a cool, dry place, away from light |
| Shelf Life | 24 months (unopened packaging) |
Function
- ●
Effective UTI Defense: D-Mannose works by preventing harmful bacteria from adhering to your urinary tract walls, effectively halting the infection right in its tracks.
- ●
Fast-Acting Relief: Experience quick relief from the painful symptoms of UTIs. Our D-Mannose formula starts working rapidly, so you can get back to feeling your best.
- ●
Gentle and Safe: Unlike antibiotics that can disrupt your body’s natural balance, D-Mannose gently supports your urinary system’s health without harming beneficial bacteria.
- ●
Natural and Pure: We take pride in providing you with the purest D-Mannose derived from premium sources. No artificial additives, just the goodness nature intended.
- ●
Prevention Made Easy: Incorporate D-Mannose into your daily routine for proactive urinary health maintenance. Stay one step ahead of recurring infections and enjoy a life of comfort.
Function:
- Effective UTI Defense: D-Mannose works by preventing harmful bacteria from adhering to your urinary tract walls, effectively halting the infection right in its tracks.
- Fast-Acting Relief: Experience quick relief from the painful symptoms of UTIs. Our D-Mannose formula starts working rapidly, so you can get back to feeling your best.
- Gentle and Safe: Unlike antibiotics that can disrupt your body’s natural balance, D-Mannose gently supports your urinary system’s health without harming beneficial bacteria.
- Natural and Pure: We take pride in providing you with the purest D-Mannose derived from premium sources. No artificial additives, just the goodness nature intended.
- Prevention Made Easy: Incorporate D-Mannose into your daily routine for proactive urinary health maintenance. Stay one step ahead of recurring infections and enjoy a life of comfort
faq
D-Mannose Powder FAQ
●
What is the pharmaceutical-grade purity level of your D-Mannose powder?
Our premium D-Mannose powder meets strict quality standards:
| Parameter | Specification |
|---|---|
| Purity (HPLC) | ≥99.5% |
| Mesh Size | 80-100 μm |
| Solubility | Water Soluble ≥98% |
| Loss on Drying | ≤0.5% |
All batches come with 3rd-party lab analysis reports.
●
Is your D-Mannose production facility GMP and ISO certified?
Yes, we maintain dual certification:
- GMP Certification No.: CN-GMP-230015
- ISO 22000:2018 Certified (Certificate ID: FSSC 004582)
- Halal Certification: MUI-HC-0324-2024
Our facility undergoes quarterly audits by SGS and Intertek.
●
What’s the recommended dosage for UTI supplement formulations?
Based on clinical research and formulation expertise:
- Preventive maintenance: 500-1000mg daily
- Acute phase support: 1500mg every 3 hours (max 6g/day)
- Combination formulas: 30-50% D-Mannose content with cranberry extract
Our technical team provides free formulation guidance for OEM clients.
●
What packaging options do you offer for bulk D-Mannose orders?
We provide pharmaceutical-grade packaging solutions:
- Standard: 25kg/drum with double PE bags + desiccant
- Custom: 1-5kg aliquots in foil bags (MOQ 500kg)
- Special: Nitrogen-flushed vacuum packaging (+15% cost)
All shipments include COA, MSDS, and shelf-life documentation.
●
How do you ensure batch-to-batch consistency?
Our quality control process includes:
- Raw material NMR fingerprint verification
- In-process testing every 200kg
- Stability studies (24 months accelerated testing)
- Traceability system with unique batch codes
View our QC workflow video.
